bone involvement in neuroblastoma

Bone Involvement in Neuroblastoma

Placental involvement in congenital neuroblastoma.

We describe two cases of congenital neuroblastoma involving the placenta and review previously reported cases. The placentae in congenital neuroblastoma have a bulky, hydropic appearance, and contain tumour cells which are confined to the fetal circulation. The tumour emboli are not macroscopically identifiable. Pathophysiological mechanisms of placental involvement by fetal and maternal malign...

Congenital neuroblastoma with placental involvement.

We describe an extremely rare case of congenital neuroblastoma with placental involvement. A fetus with a left abdominal mass detected during ultrasonography at 23 weeks' gestation developed hydrops fetalis by 26 weeks' gestation. The mother developed hypertension at 26 5/7 weeks' gestation. Based on a clinical diagnosis of pregnancy-induced hypertension, labor was induced at 26 6/7 weeks. Howe...

ppGalNAc-T13: a new molecular marker of bone marrow involvement in neuroblastoma.

BACKGROUND To identify new molecular markers of bone marrow dissemination in human neuroblastoma (NB), we studied the transcriptome profiles of malignant neuroblasts established from the human MYCN-amplified IGR-N-91 model. METHODS This experimental model includes human neuroblastoma cells derived from a subcutaneous stage 4 disease, myocardium (Myoc) and bone marrow (BM) metastatic cells. ...

Bone and Bone Marrow Involvement in Sarcoidosis

To the Editor, We report a 52-year-old male patient with bone marrow and skeletal system involvement of sarcoidosis. In sarcoidosis, while bone involvement occurs at a rate of 10%-15%, iliac bone and bone marrow involvement is less common [1,2]. A 52-year-old male patient was admitted to our clinic with increased lower back pain with activity for the last 2 months. The patient occasionally coug...

Bone marrow involvement in sarcoidosis.

A 36-year-old woman presented with joint pain and swelling, not improving with nonsteroidal anti-inflammatory drugs. Plain radiographs of feet, ankles, pelvis and lumbar spine were unremarkable. To rule out seronegative spondylarthropathy, MRI of the sacro-iliac joints (SIJ) was performed. The SIJ were normal, but multiple, nodular zones of bone marrow replacement were seen within the iliac and...